Osteofibrous dysplasia typically develops in which demographic?

Osteofibrous dysplasia is primarily a benign lesion that commonly occurs in children and adolescents. This condition is a fibro-osseous lesion often associated with the tibia and fibula, and it is characterized by the replacement of normal bone with fibrous tissue and immature bone. The peak incidence of osteofibrous dysplasia is noted in those under the age of 25, making this demographic most affected by the condition.

In contrast, the other age groups listed—adults, infants, and the elderly—are less commonly associated with this particular condition. Adults may experience other bone pathologies, infants typically have different developmental bone issues, and the elderly tend to have age-related degenerative changes rather than benign lesions like osteofibrous dysplasia. Understanding the typical demographic affected by this condition helps in making accurate diagnoses in clinical practice.